A critical step in the gene delivery is the cytosol-to- nucleustransport of exogenous DNA following initial complex uptake.
Uso de nuclear transport em inglês
1
It remains poorly understood how the nucleartransport pathway responds to increased demands for nucleocytoplasmic communication.
2
RNA interference and mutational analysis demonstrate that nucleolin is required for the nucleartransport of scuPA.
3
Mechanistically, AA inhibits nucleartransport of AR.
4
In contrast to the regulatory range of nucleartransport, the range of mRNA turnover considerably limits transcriptional wave propagation.
5
This suggests that G3BP is a nucleartransport factor, as hypothesized previously, and that viral infection may alter RNA transport.
6
Importins are adaptor molecules that physically mediate the transport of cargo molecules and comprise the third component of the nucleartransport apparatus.
7
Finally, FFS is applied to study the stoichiometry of the nucleartransport factor 2 in a cell-free system over a broad concentration range.
8
We demonstrate that z-scan FFS abolishes the brightness artifact and use the method to determine the oligomerization of cytoplasmic nucleartransport factor 2.
9
Further, we show that transfections with peptides result in an early accumulation of plasmid DNA in the nucleus of growth-arrested cells, which suggest nucleartransport.
10
Ran binding protein 1 (RanBP1) is a cytoplasmic-enriched and nuclear -cytoplasmic shuttling protein, playing important roles in nucleartransport.
11
Here we show that cisplatin treatment of head and neck cancer cells results in nucleartransport of p16 leading to a molecular modification of NFkB.
12
Nucleartransport machinery was the sole process-level discriminator of statistical significance.
13
The case is being taken by Pacific NuclearTransport Limited and French nuclear energy firm Areva, and is due to be heard today.
14
Nucleartransport of KAP-GFP could be due to a putative nuclear localization signal and nuclear export signals identified in the sea urchin KAP primary sequence.